About 9 results found for searched term "Glucosylceramide Synthase" (0.123 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M21070 | Glucosylceramide synthase-IN-2 | Glucosylceramide Synthase |
| T-690 | ||
| Glucosylceramide-IN-2 (T-690) is a potent, blood-brain barrier-transparent and orally active inhibitor of glucosylceramide synthase (GCS) with IC50s of 15 nM and 190 nM for human GCS and mouse GCS, respectively. basal and non-competitive with UDP-glucose. | ||
| M29724 | Glucosylceramide synthase-IN-1 | Glucosylceramide Synthase |
| Glucosylceramide synthase-IN-1 (T-036) a potent, brain-penetrant and orally active glucosylceramide synthase (GCS) inhibitor with IC50s of 31 nM and 51 nM for human GCS and mouse GCS, respectively. Glucosylceramide synthase-IN-1 can be used for Gaucher's disease research. | ||
| M5610 | Eliglustat | Glucosylceramide Synthase |
| GENZ-112638 | ||
| Eliglustat inhibits glucosylceramide synthase (GCS), thus reducing the load of glucosylceramide influx into the lysosome. | ||
| M5789 | Miglustat | Glucosylceramide Synthase |
| N-Butyldeoxynojirimycin; NB-DNJ; OGT918 | ||
| Miglustat(OGT918) is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1). | ||
| M9733 | Eliglustat tartrate | Others |
| Genz-112638; Eliglustat hemitartrate | ||
| Eliglustat tartrate is a potent and selective glucosylceramide synthase inhibitor with IC50 of 24 nM. | ||
| M10279 | Ibiglustat | Glucosylceramide Synthase |
| Venglustat; SAR402671; GZ402671 | ||
| Ibiglustat (Venglustat) is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. | ||
| M10310 | Miglustat hydrochloride | Glucosylceramide Synthase |
| OGT 918 HCl; NB-DNJ HCl; Miglustat HCl | ||
| Miglustat hydrochloride also known as OGT 918 and NB-DNJ, inhibits glucosylceramide synthase, and is used primarily to treat Type I Gaucher disease (GD1). | ||
| M14716 | Ibiglustat (L-Malic acid) | Glucosylceramide Synthase |
| Venglustat (L-Malic acid); SAR402671 (L-Malic acid); GZ402671 (L-Malic acid) | ||
| Ibiglustat (Venglustat) L-Malic acid is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. | ||
| M21396 | Lucerastat | Glucosylceramide Synthase |
| NB-DGJ; N-(n-Butyl)deoxygalactonojirimycin | ||
| Lucerasta is the galactose form of Miglustat, an orally active inhibitor of glucosylceramide synthase (GCS).Lucerastat has potential for use in Fabry disease research. | ||
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